Download and read online The Emperor of All Maladies in PDF and EPUB An assessment of cancer addresses both the courageous battles against the disease and the misperceptions and hubris that have compromised modern understandings, providing coverage of such topics as ancient-world surgeries and the development of present-day treatments. Reprint. Best-selling winner of the Pulitzer Prize. Includes reading-group guide.
Download and read online The Emperor of All Maladies in PDF and EPUB Winner of the Pulitzer Prize, and now a documentary from Ken Burns on PBS, The Emperor of All Maladies is a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave may have cut off her diseased breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.
Download and read online The Emperor of All Maladies in PDF and EPUB
Download and read online The Gene in PDF and EPUB THE #1 NEW YORK TIMES BESTSELLER A New York Times Notable Book A Washington Post and Seattle Times Best Book of the Year From the Pulitzer Prize-winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).
Download and read online The Laws of Medicine in PDF and EPUB Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.
Download and read online The Death of Cancer in PDF and EPUB Cancer touches everybody’s life in one way or another. But most of us know very little about how the disease works, why we treat it the way we do, and the personalities whose dedication got us where we are today. For fifty years, Dr. Vincent T. DeVita Jr. has been one of those key players: he has held just about every major position in the field, and he developed the first successful chemotherapy treatment for Hodgkin’s lymphoma, a breakthrough the American Society of Clinical Oncologists has called the top research advance in half a century of chemotherapy. As one of oncology’s leading figures, DeVita knows what cancer looks like from the lab bench and the bedside. The Death of Cancer is his illuminating and deeply personal look at the science and the history of one of the world’s most formidable diseases. In DeVita’s hands, even the most complex medical concepts are comprehensible. Cowritten with DeVita’s daughter, the science writer Elizabeth DeVita-Raeburn, The Death of Cancer is also a personal tale about the false starts and major breakthroughs, the strong-willed oncologists who clashed with conservative administrators (and one another), and the courageous patients whose willingness to test cutting-edge research helped those oncologists find potential treatments. An emotionally compelling and informative read, The Death of Cancer is also a call to arms. DeVita believes that we’re well on our way to curing cancer but that there are things we need to change in order to get there. Mortality rates are declining, but America’s cancer patients are still being shortchanged—by timid doctors, by misguided national agendas, by compromised bureaucracies, and by a lack of access to information about the strengths and weaknesses of the nation’s cancer centers. With historical depth and authenticity, DeVita reveals the true story of the fight against cancer. The Death of Cancer is an ambitious, vital book about a life-and-death subject that touches us all.
Download and read online A Cancer in the Family in PDF and EPUB A Kirkus Best Book of 2016 Oncologist and cancer gene hunter Theo Ross delivers the first authoritative, go-to for people facing a genetic predisposition for cancer There are 13 million people with cancer in the United States, and it’s estimated that about 1.3 million of these cases are hereditary. Yet despite advanced training in cancer genetics and years of practicing medicine, Dr. Theo Ross was never certain whether the history of cancers in her family was simple bad luck or a sign that they were carriers of a cancer-causing genetic mutation. Then she was diagnosed with melanoma, and for someone with a dark complexion, melanoma made no sense. It turned out there was a genetic factor at work. Using her own family’s story, the latest science of cancer genetics, and her experience as a practicing physician, Ross shows readers how to spot the patterns of inherited cancer, how to get tested for cancer-causing genes, and what to do if you have one. With a foreword by Siddartha Mukherjee, prize winning author of The Emperor of All Maladies, this will be the first authoritative, go-to for people facing inherited cancer, this book empowers readers to face their genetic heritage without fear and to make decisions that will keep them and their families healthy.
Download and read online The Cancer Chronicles in PDF and EPUB When the woman he loved was diagnosed with a metastatic cancer, science-writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is that a revolution is now under way – an explosion of new ideas about what cancer really is and where it comes from. He combs through the realms of epidemiology, clinical trials, laboratory experiments and scientific hypotheses, to reveal what we know and don’t know about cancer, showing why a cure remains such a slippery concept. His luminous accounts describe tumors that evolve like alien creatures inside the body, paleo-oncologists who uncover petrified tumors clinging to the skeletons of dinosaurs and ancient human ancestors, and the surprising reversals in science’s comprehension of the causes of cancer, with the foods we eat and environmental toxins playing a lesser role. Perhaps most fascinating of all is how cancer borrows natural processes involved in the healing of a wound or the unfolding of a human embryo and turns them against the body. Throughout his pursuit, Johnson illuminates the human experience with elegiac grace, bearing witness to the punishing gauntlet of consultations, surgeries, targeted therapies and other treatments. Provocative and intellectually vibrant, The Cancer Chronicles will challenge everything you thought you knew about the disease – and provide hope for tomorrow and the future.
Download and read online Better in PDF and EPUB The struggle to perform well is universal, but nowhere is this drive to do better more important than in medicine. In his new book, Atul Gawande explores how doctors strive to close the gap between best intentions and best performance in the face of obstacles that sometimes seem insurmountable. His vivid stories take us to battlefield surgical tents in Iraq, to a polio outbreak in India and to malpractice courtrooms around the country. He discusses the ethical dilemmas of doctors' participation in lethal injections, examines the influence of money on modern medicine and recounts the astoundingly contentious history of hand-washing. Finally, he gives a brutally honest insight into life as a practising surgeon. Unflinching but compassionate, Gawande's investigation into medical professionals and their progression from good to great provides a detailed blueprint for success that can be used by everyone.
Download and read online Complications in PDF and EPUB The international bestseller from the author of Being Mortal In these gripping accounts of true cases, bestselling author Atul Gawande performs exploratory surgery on medicine itself, laying bare a science not in its idealised form, but as it actually is - complicated, perplexing and profoundly human. This is a stunningly well-written account of the life of a surgeon: what it is like to cut into people's bodies and the terrifying - literally life and death - decisions that have to be made: operations that go wrong; of doctors who go to the bad; why autopsies are necessary; what it feels like to insert your knife into someone. 'Written as tautly as a thriller' Observer
Download and read online The Biology of Cancer Second Edition in PDF and EPUB Thoroughly updated and incorporating the most important advances in the fast-growing field of cancer biology, The Biology of Cancer, Second Edition, maintains all of its hallmark features admired by students, instructors, researchers, and clinicians around the world. The Biology of Cancer is a textbook for students studying the molecular and cellular bases of cancer at the undergraduate, graduate, and medical school levels. The principles of cancer biology are presented in an organized, cogent, and in-depth manner. The clarity of writing, supported by an extensive full-color art program and numerous pedagogical features, makes the book accessible and engaging. The information unfolds through the presentation of key experiments that give readers a sense of discovery and provide insights into the conceptual foundation underlying modern cancer biology.
Download and read online Summary Study Guide of the Emperor of All Maladies by Siddhartha Mukherjee in PDF and EPUB This guide is an UNOFFICIAL summary of the book, "The Emperor of All Maladies: A Biography of Cancer," by Siddhartha Mukherjee. It is a supplement to the original book, to make its main ideas easier to understand and put to practice. Siddhartha Mukherjee's The Emperor of All Maladies chronicles a fascinating "biography" of cancer - from its first documented appearance five thousand years ago through the battles in the 20th century to cure, control, and subdue it, to a radical new understanding of its biology - its essence. The book recounts the centuries of discoveries, successes, and failures in the cat and mouse battle against cancer, bringing cancer research and cancer biology to the lay public. The purpose of this guide is to help you understand and practice the ideas described in the book. It includes: A compact summary of the original book. The summary will help you understand the key ideas and recommendations. It helps you master the concept while offering a rapid refresher when you need it most. Use it to keep the topic relevant and in front of you for times you fall off track. It'll save you precious time rereading the book to reabsorb, remember and re-categorize. We did the work for you; and Online Videos. These are extra learning materials such as on-demand replay of public lectures, and seminars. They help reinforce your understanding of the ideas and make them easier to put to practice. This study guide is more than a book summary: use it as a supplement to the book to make the ideas easier to understand and put to practice. Tags: Leukemia; childhood leukemia; cancer; radiation; chemotherapy; magic bullet; mustard gas; radical mastectomy; oncology; chemotherapeutic; chemotherapist; radium; breast cancer; lung cancer; tobacco; national cancer act; war on cancer; vamp; hodgkin's disease; lumpectomy; simple mastectomy; adjuvant therapy; bone marrow; transplantation; pap smear; mammography; mammogram; genes; genetic; hormone therapy; Herceptin; gleevec; genentech;
Download and read online The Truth in Small Doses in PDF and EPUB A “brilliant” (Fortune), eye-opening history of the war on cancer, The Truth in Small Doses asks why we are losing this essential fight and charts a path forward. Over the past half century, deaths from heart disease, stroke, and so many other killers have fallen dramatically. But cancer continues to kill with abandon. In 2013, despite a four-decade “war” against the disease that has cost hundreds of billions of dollars, more than 1.6 million Americans will be diagnosed with cancer and nearly six hundred thousand will die from it. A decade ago, Clifton Leaf, a celebrated journalist and a cancer survivor himself, began to investigate why we had made such limited progress fighting this terrifying disease. The result is a gripping narrative that reveals why the public’s immense investment in research has been badly misspent, why scientists seldom collaborate and share their data, why new drugs are so expensive yet routinely fail, and why our best hope for progress—brilliant young scientists—are now abandoning the search for a cure. “Through flowing prose Leaf delivers, alongside facts and data, stories on personalities involved in research, the fascinating process of solving an unusual and highly deadly cancer in Africa, and the heartbreaking realities of cancer treatment in children today. Leaf’s extensively investigated treatise will resonate with researchers and patients frustrated by the bureaucratic woes he delineates. Public policy makers, grant reviewers, and pharmaceutical researchers alike must consider Leaf’s indictment and proposed solutions” (Publishers Weekly). The Truth in Small Doses is that rare tale that will both outrage readers and inspire conversation and change.
Download and read online Cancer in PDF and EPUB In this lucid and entertaining book, Mel Greaves argues that evolutionary biology offers a new perspective that can help us unravel the riddle of cancer. Why, for example, have women always had such a raw deal in the cancer stakes? And why are some cancers, such as prostate cancer, increasing in incidence? Greaves argues that Darwinian selection millions of years ago has endowed our genes and cells with inherently cancerous credentials, and this is exacerbated by our rapid social evolution and exotic behavioural traits that outpace genetic adaptation. The book is full of novel insights, the latest scientific discoveries, and wonderful historical anecdotes. It provides a unique portrait of cancer, past, present, and future.
Download and read online Heal in PDF and EPUB Man's best friend could help cure man's greatest scourge Drawn from extensive research, on-the-ground reporting, and personal experience, this book explores the fascinating role dogs are playing in the search for cures for cancer. Learn how veterinarians and oncologists are working together to discover new treatments — cutting-edge therapies designed to help both dogs and people suffering from cancer. Heal introduces readers to the field of comparative oncology by describing several research projects aimed at finding new therapies for cancers that are similar in dogs and people, including lymphoma, osteosarcoma, breast cancer, melanoma, and gastric cancer. Weintraub, who lost her sister to gastric cancer, also writes about the emerging science behind the remarkable ability of dogs to sniff out early stage cancer and the efforts underway to translate that talent into diagnostic devices for early detection of the disease. In the course of bringing these dogs and their human companions to life, Weintraub takes her own personal journey from grief to healing, as she shows her readers how man's best friend might be the key to unlocking the mysteries of cancer.