Download and read online The Emperor of All Maladies in PDF and EPUB An assessment of cancer addresses both the courageous battles against the disease and the misperceptions and hubris that have compromised modern understandings, providing coverage of such topics as ancient-world surgeries and the development of present-day treatments. Reprint. Best-selling winner of the Pulitzer Prize. Includes reading-group guide.
Download and read online The Emperor of All Maladies in PDF and EPUB Winner of the Pulitzer Prize, and now a documentary from Ken Burns on PBS, The Emperor of All Maladies is a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence. Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave may have cut off her diseased breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.
Download and read online The Gene in PDF and EPUB THE #1 NEW YORK TIMES BESTSELLER A New York Times Notable Book A Washington Post and Seattle Times Best Book of the Year From the Pulitzer Prize-winning author of The Emperor of All Maladies—a fascinating history of the gene and “a magisterial account of how human minds have laboriously, ingeniously picked apart what makes us tick” (Elle). “Dr. Siddhartha Mukherjee dazzled readers with his Pulitzer Prize-winning The Emperor of All Maladies in 2010. That achievement was evidently just a warm-up for his virtuoso performance in The Gene: An Intimate History, in which he braids science, history, and memoir into an epic with all the range and biblical thunder of Paradise Lost” (The New York Times). In this biography Mukherjee brings to life the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices. “Mukherjee expresses abstract intellectual ideas through emotional stories…[and] swaddles his medical rigor with rhapsodic tenderness, surprising vulnerability, and occasional flashes of pure poetry” (The Washington Post). Throughout, the story of Mukherjee’s own family—with its tragic and bewildering history of mental illness—reminds us of the questions that hang over our ability to translate the science of genetics from the laboratory to the real world. In riveting and dramatic prose, he describes the centuries of research and experimentation—from Aristotle and Pythagoras to Mendel and Darwin, from Boveri and Morgan to Crick, Watson and Franklin, all the way through the revolutionary twenty-first century innovators who mapped the human genome. “A fascinating and often sobering history of how humans came to understand the roles of genes in making us who we are—and what our manipulation of those genes might mean for our future” (Milwaukee Journal-Sentinel), The Gene is the revelatory and magisterial history of a scientific idea coming to life, the most crucial science of our time, intimately explained by a master. “The Gene is a book we all should read” (USA TODAY).
Download and read online The Laws of Medicine in PDF and EPUB Essential, required reading for doctors and patients alike: A Pulitzer Prize-winning author and one of the world’s premiere cancer researchers reveals an urgent philosophy on the little-known principles that govern medicine—and how understanding these principles can empower us all. Over a decade ago, when Siddhartha Mukherjee was a young, exhausted, and isolated medical resident, he discovered a book that would forever change the way he understood the medical profession. The book, The Youngest Science, forced Dr. Mukherjee to ask himself an urgent, fundamental question: Is medicine a “science”? Sciences must have laws—statements of truth based on repeated experiments that describe some universal attribute of nature. But does medicine have laws like other sciences? Dr. Mukherjee has spent his career pondering this question—a question that would ultimately produce some of most serious thinking he would do around the tenets of his discipline—culminating in The Laws of Medicine. In this important treatise, he investigates the most perplexing and illuminating cases of his career that ultimately led him to identify the three key principles that govern medicine. Brimming with fascinating historical details and modern medical wonders, this important book is a fascinating glimpse into the struggles and Eureka! moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee’s signature eloquence and passionate prose, The Laws of Medicine is a critical read, not just for those in the medical profession, but for everyone who is moved to better understand how their health and well-being is being treated. Ultimately, this book lays the groundwork for a new way of understanding medicine, now and into the future.
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Download and read online The Death of Cancer in PDF and EPUB Cancer touches everybody’s life in one way or another. But most of us know very little about how the disease works, why we treat it the way we do, and the personalities whose dedication got us where we are today. For fifty years, Dr. Vincent T. DeVita Jr. has been one of those key players: he has held just about every major position in the field, and he developed the first successful chemotherapy treatment for Hodgkin’s lymphoma, a breakthrough the American Society of Clinical Oncologists has called the top research advance in half a century of chemotherapy. As one of oncology’s leading figures, DeVita knows what cancer looks like from the lab bench and the bedside. The Death of Cancer is his illuminating and deeply personal look at the science and the history of one of the world’s most formidable diseases. In DeVita’s hands, even the most complex medical concepts are comprehensible. Cowritten with DeVita’s daughter, the science writer Elizabeth DeVita-Raeburn, The Death of Cancer is also a personal tale about the false starts and major breakthroughs, the strong-willed oncologists who clashed with conservative administrators (and one another), and the courageous patients whose willingness to test cutting-edge research helped those oncologists find potential treatments. An emotionally compelling and informative read, The Death of Cancer is also a call to arms. DeVita believes that we’re well on our way to curing cancer but that there are things we need to change in order to get there. Mortality rates are declining, but America’s cancer patients are still being shortchanged—by timid doctors, by misguided national agendas, by compromised bureaucracies, and by a lack of access to information about the strengths and weaknesses of the nation’s cancer centers. With historical depth and authenticity, DeVita reveals the true story of the fight against cancer. The Death of Cancer is an ambitious, vital book about a life-and-death subject that touches us all.
Download and read online Guide to Siddhartha Mukherjee s the Emperor of All Maladies in PDF and EPUB PLEASE NOTE: THIS IS A GUIDE TO THE ORIGINAL BOOK. Guide to Siddhartha Mukherjee's The Emperor of All Maladies Preview: Scientist and physician Siddhartha Mukherjee, author of The Emperor of All Maladies, calls his book a biography of cancer rather than simply a history. The author explores a wide range of research, historical accounts, and personal stories in this intensive look at the backstory of cancer. This includes the evolution of cancer's nature, treatment, and the scientific and medical communities' understanding of the disease as well as the support of the public and politicians in the crucial fight to find a cure... Inside this companion: -Overview of the book -Important People -Key Insights -Analysis of Key Insights
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Download and read online A Cancer in the Family in PDF and EPUB A Kirkus Best Book of 2016 Oncologist and cancer gene hunter Theo Ross delivers the first authoritative, go-to for people facing a genetic predisposition for cancer There are 13 million people with cancer in the United States, and it’s estimated that about 1.3 million of these cases are hereditary. Yet despite advanced training in cancer genetics and years of practicing medicine, Dr. Theo Ross was never certain whether the history of cancers in her family was simple bad luck or a sign that they were carriers of a cancer-causing genetic mutation. Then she was diagnosed with melanoma, and for someone with a dark complexion, melanoma made no sense. It turned out there was a genetic factor at work. Using her own family’s story, the latest science of cancer genetics, and her experience as a practicing physician, Ross shows readers how to spot the patterns of inherited cancer, how to get tested for cancer-causing genes, and what to do if you have one. With a foreword by Siddartha Mukherjee, prize winning author of The Emperor of All Maladies, this will be the first authoritative, go-to for people facing inherited cancer, this book empowers readers to face their genetic heritage without fear and to make decisions that will keep them and their families healthy.
Download and read online Summary Study Guide of the Emperor of All Maladies by Siddhartha Mukherjee in PDF and EPUB This guide is an UNOFFICIAL summary of the book, "The Emperor of All Maladies: A Biography of Cancer," by Siddhartha Mukherjee. It is a supplement to the original book, to make its main ideas easier to understand and put to practice. Siddhartha Mukherjee's The Emperor of All Maladies chronicles a fascinating "biography" of cancer - from its first documented appearance five thousand years ago through the battles in the 20th century to cure, control, and subdue it, to a radical new understanding of its biology - its essence. The book recounts the centuries of discoveries, successes, and failures in the cat and mouse battle against cancer, bringing cancer research and cancer biology to the lay public. The purpose of this guide is to help you understand and practice the ideas described in the book. It includes: A compact summary of the original book. The summary will help you understand the key ideas and recommendations. It helps you master the concept while offering a rapid refresher when you need it most. Use it to keep the topic relevant and in front of you for times you fall off track. It'll save you precious time rereading the book to reabsorb, remember and re-categorize. We did the work for you; and Online Videos. These are extra learning materials such as on-demand replay of public lectures, and seminars. They help reinforce your understanding of the ideas and make them easier to put to practice. This study guide is more than a book summary: use it as a supplement to the book to make the ideas easier to understand and put to practice. Tags: Leukemia; childhood leukemia; cancer; radiation; chemotherapy; magic bullet; mustard gas; radical mastectomy; oncology; chemotherapeutic; chemotherapist; radium; breast cancer; lung cancer; tobacco; national cancer act; war on cancer; vamp; hodgkin's disease; lumpectomy; simple mastectomy; adjuvant therapy; bone marrow; transplantation; pap smear; mammography; mammogram; genes; genetic; hormone therapy; Herceptin; gleevec; genentech;
Download and read online The Cancer Chronicles in PDF and EPUB When the woman he loved was diagnosed with a metastatic cancer, science-writer George Johnson embarked on a journey to learn everything he could about the disease and the people who dedicate their lives to understanding and combating it. What he discovered is that a revolution is now under way – an explosion of new ideas about what cancer really is and where it comes from. He combs through the realms of epidemiology, clinical trials, laboratory experiments and scientific hypotheses, to reveal what we know and don’t know about cancer, showing why a cure remains such a slippery concept. His luminous accounts describe tumors that evolve like alien creatures inside the body, paleo-oncologists who uncover petrified tumors clinging to the skeletons of dinosaurs and ancient human ancestors, and the surprising reversals in science’s comprehension of the causes of cancer, with the foods we eat and environmental toxins playing a lesser role. Perhaps most fascinating of all is how cancer borrows natural processes involved in the healing of a wound or the unfolding of a human embryo and turns them against the body. Throughout his pursuit, Johnson illuminates the human experience with elegiac grace, bearing witness to the punishing gauntlet of consultations, surgeries, targeted therapies and other treatments. Provocative and intellectually vibrant, The Cancer Chronicles will challenge everything you thought you knew about the disease – and provide hope for tomorrow and the future.
Download and read online Cancer as a Metabolic Disease in PDF and EPUB The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.
Download and read online The Evil Hours in PDF and EPUB In the tradition of The Emperor of All Maladies and The Noonday Demon, a moving, eye-opening exploration of PTSD Just as polio loomed over the 1950s, and AIDS stalked the 1980s and ’90s, posttraumatic stress disorder haunts us in the early years of the twenty-first century. Over a decade into the United States’ “global war on terror,” PTSD afflicts as many as 30 percent of the conflict’s veterans. But the disorder’s reach extends far beyond the armed forces. In total, some twenty-seven million Americans are believed to be PTSD survivors. Yet to many of us, the disorder remains shrouded in mystery, secrecy, and shame. Now, David J. Morris — a war correspondent, former Marine, and PTSD sufferer himself — has written the essential account of this illness. Through interviews with individuals living with PTSD, forays into the scientific, literary, and cultural history of the illness, and memoir, Morris crafts a moving work that will speak not only to those with the condition and to their loved ones, but also to all of us struggling to make sense of an anxious and uncertain time.
Download and read online Stiff in PDF and EPUB What happens to your body after you have died? Fertilizer? Crash Test Dummy? Human Dumpling? Ballistics Practise? Life after death is not as simple as it looks. Mary Roach's Stiff lifts the lid off what happens to our bodies once we have died. Bold, original and with a delightful eye for detail, Roach tells us everything we wanted to know about this new frontier in medical science. Interweaving present-day explorations with a history of past attempts to study what it means to be human Stiff is a deliciously dark investigations for readers of popular science as well as fans of the macabre
Download and read online Toms River in PDF and EPUB WINNER OF THE PULITZER PRIZE • Winner of The New York Public Library’s Helen Bernstein Book Award • “A new classic of science reporting.”—The New York Times The riveting true story of a small town ravaged by industrial pollution, Toms River melds hard-hitting investigative reporting, a fascinating scientific detective story, and an unforgettable cast of characters into a sweeping narrative in the tradition of A Civil Action, The Emperor of All Maladies, and The Immortal Life of Henrietta Lacks. One of New Jersey’s seemingly innumerable quiet seaside towns, Toms River became the unlikely setting for a decades-long drama that culminated in 2001 with one of the largest legal settlements in the annals of toxic dumping. A town that would rather have been known for its Little League World Series champions ended up making history for an entirely different reason: a notorious cluster of childhood cancers scientifically linked to local air and water pollution. For years, large chemical companies had been using Toms River as their private dumping ground, burying tens of thousands of leaky drums in open pits and discharging billions of gallons of acid-laced wastewater into the town’s namesake river. In an astonishing feat of investigative reporting, prize-winning journalist Dan Fagin recounts the sixty-year saga of rampant pollution and inadequate oversight that made Toms River a cautionary example for fast-growing industrial towns from South Jersey to South China. He tells the stories of the pioneering scientists and physicians who first identified pollutants as a cause of cancer, and brings to life the everyday heroes in Toms River who struggled for justice: a young boy whose cherubic smile belied the fast-growing tumors that had decimated his body from birth; a nurse who fought to bring the alarming incidence of childhood cancers to the attention of authorities who didn’t want to listen; and a mother whose love for her stricken child transformed her into a tenacious advocate for change. A gripping human drama rooted in a centuries-old scientific quest, Toms River is a tale of dumpers at midnight and deceptions in broad daylight, of corporate avarice and government neglect, and of a few brave individuals who refused to keep silent until the truth was exposed. NAMED ONE OF THE BEST BOOKS OF THE YEAR BY NPR AND KIRKUS REVIEWS “A thrilling journey full of twists and turns, Toms River is essential reading for our times. Dan Fagin handles topics of great complexity with the dexterity of a scholar, the honesty of a journalist, and the dramatic skill of a novelist.”—Siddhartha Mukherjee, M.D., author of the Pulitzer Prize–winning The Emperor of All Maladies “A complex tale of powerful industry, local politics, water rights, epidemiology, public health and cancer in a gripping, page-turning environmental thriller.”—NPR “Unstoppable reading.”—The Philadelphia Inquirer “Meticulously researched and compellingly recounted . . . It’s every bit as important—and as well-written—as A Civil Action and The Immortal Life of Henrietta Lacks.”—The Star-Ledger “Fascinating . . . a gripping environmental thriller.”—Kirkus Reviews (starred review) “An honest, thoroughly researched, intelligently written book.”—Slate “[A] hard-hitting account . . . a triumph.”—Nature “Absorbing and thoughtful.”—USA Today From the Hardcover edition.